发表论文
我们在海洋生物学、生物膜科学和环境生物技术方面的研究贡献。
47Publications
1000+Citations
Research Article
A noncanonical intrinsic terminator in the HicAB toxin–antitoxin operon promotes the transmission of conjugative antibiotic resistance plasmids
Lin J, Ni S, Li B, Guo Y, Gao X, Liu Y, Yi L, Wang P, Chen R, Yao J, Wood TK, Wang X*
Nucleic Acids Research53(5)(2025)
Research Article
Crosstalk Between Inovirus Core Gene and Accessory Toxin-Antitoxin System Mediates Polylysogeny
Gu J, Weng J, Lin S, Guo Y, Liu Y, Wang X*
Nature Communications(2025)
Status: accepted
Research Article
Inovirus-Encoded Peptides Induce Specific Toxicity in Pseudomonas aeruginosa
Weng J, Guo, Y*, Gu, J, Chen R, Wang X*
Viruses17, 112(2025)
Research Article
High temperatures increase the virulence of Vibrio bacteria towards their coral host and competing bacteria via type VI secretion systems
Wang W, Tang K, Wang X*
PLoS Biology22(9): e3002788(2024)
Research Article
A reverse transcriptase controls prophage genome reduction to promote phage dissemination in Pseudomonas aeruginosa biofilms
Guo Y., Lin S., Chen R., Tang K., Zhao N., Waldor, MW, Wang X*
Cell Reports43: 114883(2024)
Research Article
Control of lysogeny and antiphage defense by a prophage-encoded kinase-phosphatase module
Guo, Y., Tang, K., Sit, B., Gu, J., Chen, R., Lin, J., Lin, S., Liu, X., Wang, W., Gao, X., Liu T., Liu F., Luo HR, Waldor, MW*, Wang X*
Nature Communications15, 7244(2024)
Research Article
A nuclease domain fused to the Snf2 helicase confers antiphage defence in coral-associated Halomonas meridiana
Liu, T., Gao, X., Chen, R., Tang, K., Liu, Z., Wang, P., Wang X*
Microbial Biotechnology17, e14524(2024)
Research Article
The histone-like nucleoid-structuring protein encoded by the plasmid pMBL6842 regulates both plasmid stability and host physiology of Pseudoalteromonas rubra SCSIO 6842
Li B, Ni S, Liu Y, Lin J, Wang X*
Microbiological Research286:127817(2024)
Research Article
Active prophages in coral-associated Halomonas capable of lateral transduction
Liu ZY, Tang KH*, Zhou YQ, Liu TL, Guo YX, Wu DT, Wang X*
The ISME Journal18: 1, wrae085(2024)
Research Article
Acetylation of xenogeneic silencer H-NS regulates biofilm development through the nitrogen homeostasis regulator in Shewanella
Liu X, Li J, Zhang Z, He Y, Wang M, Zhao Y, Lin S, Liu T, Liao Y, Zhang N, Yuan K, Ling Y, Liu Z, Chen X, Chen Z, Chen R, Wang X*, Gu B*
Nucleic Acids Research(2024)
Research Article
Applications of toxin-antitoxin systems in synthetic biology
Lin J, Guo Y, Yao J, Tang K, Wang X*
Engineering Microbiology3:2 2667-3703(2023)
Research Article
Minimized antibiotic-free plasmid vector for gene therapy utilizing a new toxin-antitoxin system
Chen Z#, Yao J#*, Zhang P, Wang P, Ni SW, Liu T, Zhao Y, Tang K, Sun Y, Qian Q, Wang X*
Metabolic Engineering79, 86-96(2023)
Research Article
The coral pathogen Vibrio coralliilyticus kills non-pathogenic holobiont competitors by triggering prophage induction
Wang WQ, Tang KH, Wang PX, Zeng ZS, Xu T, Zhan WE, Liu TL, Wang Y, Wang X*
Nature Ecology & Evolution6: 1132–1144(2022)
Research Article
Mobile genetic elements used by competing coral microbial populations increase genomic plasticity
Wang PX, Zhao Y, Wang WQ, Lin ST, Tang KH, Liu TL, Wood TK, Wang X*
ISME Journal16, 2220–2229(2022)
Research Article
Filamentous prophage capsid proteins contribute to superinfection exclusion in Pseudomonas aeruginosa
Wang WQ#, Li YM#, Tang KH, Lin JZ, Gao XY, Guo YX*, Wang X*
Environmental Microbiology(2022)
Research Article
Prophage Tracer: precisely tracing prophages in prokaryotic genomes using overlapping split-read alignment
Tang K, Wang W, Sun Y, Zhou Y, Wang P, Guo Y, Wang X*
Nucleic Acids Research16;49(22): e128(2021)
Research Article
Conjugative plasmid-encoded toxin-antitoxin system PrpT/PrpA directly controls plasmid copy number
Ni SW, Li BY, Tang KH, Yao JY, Wood TK, Wang PX*, Wang X*
PNAS118 (4) e2011577118(2021)
Research Article
Xenogeneic silencing relies on temperature dependent phosphorylation of the host H-NS protein in Shewanella
Liu X, Lin S, Liu T, Zhou Y, Wang W, Yao J, Guo Y, Tang K, Chen R, Benedik MJ, Wang X*
Nucleic Acids Research49(6) :3427-3440(2021)
Research Article
Type VII Toxin/Antitoxin Classification System for Antitoxins that Enzymatically Neutralize Toxins
Wang X*, Yao JY, Sun YC, Wood TK*
Trends in Microbiology29(5):388-393(2021)
Research Article
Novel Polyadenylylation-Dependent Neutralization Mechanism of the HEPN/MNT Toxin/Antitoxin System
Yao JY, Zhen XK, Tang KH, Liu LT, Xu XL, Chen Z, Guo YX., Liu XX., Wood TK, Ouyang SY*, Wang X*
Nucleic Acids Research48(19): 11054–11067(2020)
Research Article
Identification of bacteria-derived urease in the coral gastric cavity
Zhou Y., Tang KH*, Wang PX, Wang WQ, Wang Y, Wang X*
SCIENCE CHINA Earth Sciences63(10): 1553-1563(2020)
Research Article
Prophage encoding toxin/antitoxin system PfiT/PfiA inhibits Pf4 production in Pseudomonas aeruginosa
Li YM, Liu XX, Tang KH, Wang W, Guo YX*, Wang X*
Microbial Biotechnology13(4):1132-1144(2020)
Research Article
Symbiosis of a P2-Family Phage and Deep-Sea Shewanella putrefaciens
Liu X, Tang KH, Zhang DL, Li YM, Liu Z, Yao J, Wood TK, Wang X*
Environmental Microbiology21(11):4212-4232(2019)
Research Article
Molybdenum-mediated chemotaxis of Pseudoalteromonas lipolytica enhances biofilm-Induced mineralization on low alloy steel surface
Guo ZW, Wang WQ, Guo N, Zeng ZS, Liu T*, Wang X*
Corrosion Science159: 108123(2019)
Research Article
Eliminating mcr-1-harbouring plasmids in clinical isolates using the CRISPR/Cas9 system
PX Wang, D He, BY Li, YX Guo, WQ Wang, XJ Luo, XY Zhao, Wang X*
Journal of Antimicrobial Chemotherapy74(9), 2559–2565(2019)
Research Article
Antitoxin HigA inhibits virulence gene mvfR expression in Pseudomonas aeruginosa
Guo YX, Sun CL, Li YM, Tang KH, Ni SW, Wang X*
Environmental Microbiology21(8):2707-2723(2019)
Research Article
Phage Mediate Bacterial Self-Recognition
Song S, Guo YX, Kim JB, Wang X*, Wood TK*
Cell Reports27 (3), 737-749(2019)
Research Article
Characterization of Two Toxin-Antitoxin Systems in Deep-Sea Streptomyces sp. SCSIO 02999
Zhan WE, Yao JY, Tang KH, Li YM, Guo YX*, Wang X*
Marine Drugs17(4), 211(2019)
Research Article
Recent progress on signalling molecules of coral-associated microorganisms
Tang KH, Wang Y, Wang X*
SCIENCE CHINA Earth Sciences62 (4), 609618(2019)
Research Article
Excisionase in Pf Filamentous Prophage Controls Lytic-lysogeny Decision-making in Pseudomonas aeruginosa
Li Y, Liu X, Tang KH, Wang PX, Zeng ZS, Guo YX, Wang X*
Molecular Microbiology111(2), 495–513(2019)
Research Article
Biofilm formation in Pseudoalteromonas lipolytica is related to IS5-like insertions in the capsular polysaccharide operon
Zeng, Z., Zhan, W., Wang, W., Wang, P., Tang, K., Wang X*
FEMS Microbiology Ecology95(6)(2019)
Research Article
Marine Bacteria Provide Lasting Anti-Corrosion Activity for Steel via Biofilm-induced Mineralization
Liu T, Guo ZW, Zeng ZS, Guo N, Lei YH, Liu T, Sun SB, Chang XT, Yin YS*, Wang X*
ACS Applied Materials & Interfaces10 (46), 40317–40327(2018)
Research Article
Type II toxin/antitoxin system ParESO /CopASO stabilizes prophage CP4So in Shewanella oneidensis
Yao J, Guo Y, Wang P, Zeng Z, Li B, Tang K, Liu X, Wang X*
Environmental Microbiology20, 1224-1239(2018)
Research Article
Structure-function analyses reveal the molecular architecture and neutralization mechanism of a bacterial HEPN-MNT toxin-antitoxin
Jia X, Yao J, Gao Z, Liu G, Dong Y, Wang X* and Zhang H*
Journal of Biological Chemistry293, 6812-6823(2018)
Research Article
Dissemination and loss of a biofilm-related genomic island in marine Pseudoalteromonas mediated by integrative and conjugative elements
Wang P, Zeng Z, Wang W, Wen Z, Li J, Wang X*
Environmental Microbiology19(11), 4620-4637(2017)
Research Article
Tail-anchored inner membrane protein ElaB increases resistance to stress while reducing persistence in Escherichia coli
Guo Y, Liu X, Li B, Yao J, Wood TK, Wang X*
Journal of Bacteriology199: e00057-17(2017)
Research Article
Cold adaptation regulated by cryptic prophage excision in Shewanella oneidensis
Zeng Z, Liu X, Yao J, Guo Y, Li B, Li Y, Jiao N, Wang X*
ISME Journal10(12):2787-2800(2016)
Research Article
Cryptic prophages as targets for drug development
Wang X*, Wood TK*
Drug Resistance Updates27:30-8(2016)
Research Article
Development of an efficient conjugation-based genetic manipulation system for Pseudoalteromonas
Wang PX, Yu ZC, Li BY, Cai XS, Zeng ZZ, Chen X, Wang X*
Microbial Cell Factories14:11(2015)
Research Article
RalR (a DNase) and RalA (a small RNA) form a type I toxin–antitoxin system in Escherichia coli
Guo Y, Quiroga C, Chen Q, McAnulty MJ, Benedik MJ, Wood TK*, Wang X*
Nucleic Acids Research42 (10): 6448-6462(2014)
Research Article
Type II toxin/antitoxin MqsR/MqsA controls type V toxin/antitoxin GhoT/GhoS
Wang X*, Lord DM, Hong SH, Peti W, Benedik MJ, Page R, Wood TK*
Environmental Microbiology15(6):1734-44(2013)
Research Article
A new type V toxin-antitoxin system where mRNA for toxin GhoT is cleaved by antitoxin GhoS
Wang X#, Lord DM#, Cheng HY#, Osbourne DO, Hong SH, Sanchez-Torres V, Quiroga C, Zheng K, Herrmann T, Peti W, Benedik MJ, Page R*, Wood TK*
Nature Chemical Biology8(10):855-61(2012)
Research Article
Antitoxin MqsA helps mediate the bacterial general stress response
Wang X, Kim Y, Hong SH, Ma Q, Brown BL, Pu M, Tarone AM, Benedik MJ, Peti W, Page R, Wood TK*
Nature Chemical Biology7, 359-366(2011)
Research Article
Toxin/antitoxin systems influence biofilm and persister cell formation and the general stress response
Wang X, Wood TK*
Applied and Environmental Microbiology77, 5577-5583(2011)
Research Article
IS5 inserts upstream of flhDC in a quasi-Lamarckian way
Wang X, Wood TK*
ISME Journal5, 15171525(2011)
Research Article
Cryptic prophages help bacteria cope with adverse environments
Wang X, Kim Y, Ma Q, Hong S-H, Pokusaeva K, Sturnio JM, Wood TK*
Nature Communications1, 147(2010)
Research Article
Control and benefits of CP4-57 prophage excision in Escherichia coli biofilms
Wang X, Kim Y, Wood TK*
ISME Journal3, 1164-1179(2009)